- Desloratadine ;
456 р. Average price online * 456 p.
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Instructions for use
Syrup is allowed for children from 1 year.
Tablets are allowed for adults and children from 12 years.
Indications for use
The drug "Erius" is prescribed for:
- allergic rhinitis (the drug fights mucus, sneezing, nasal congestion, itching, redness of the eyes, watery eyes);
- urticaria (medication helps to get rid of pruritus, rash);
- atopic dermatitis in children and adults ;
- allergic dermatitis and other dermatoses with an allergic nature.
Algorithm of application and dose
Adults and children from 12 years of age are prescribed 1 tablet (5 mg) once a day.
Medication is taken regardless of the meal, but at the same time. The tablet is not chewed and drank plenty of water. The duration of treatment depends on the severity of the disease and how it proceeds.
If the symptoms of allergic rhinitis disappear, then the drug is discontinued. However, the treatment should be resumed when the disease recurs. Tablets can also be assigned continuously, but only for the period when the patient comes in contact with the allergen.
Permissible daily dose for children:
- 1-5 years - 1.25 mg;
- 6-11 years old - 2.5 mg;
- from 12 years old - 5 mg.
The permissible daily dose for adults is 5 mg (10 ml).
Reception of syrup is carried out irrespective of meal.
The drug "Erius" is contraindicated in patients who have an increased sensitivity of the body to certain components of the drug, as it can provoke life-threatening reactions of individual intolerance to the drug of allergic or non-allergic origin.
Since Erius is eliminated from the body along with urine, patients suffering from severe kidney disease and impairment of their functions should take this drug with heightened caution and only when prescribed by a doctor.
Syrup in its composition contains simple sugars that can have a negative impact on people with certain hereditary diseases.
Increased fatigue, headache, dry mouth are not excluded.
It is extremely rare to observe tachycardia, palpitations, allergic reactions (including anaphylaxis and rash), an increase in the concentration of bilirubin and the activity of liver enzymes.
Syrup can affect side effects such as diarrhea, fever, insomnia. Adolescents and adults note fatigue, headache, dry mouth.
In more rare cases, patients complain of dizziness, drowsiness, palpitations, tachycardia, nausea, vomiting, abdominal pain, diarrhea, allergic reactions (angioedema, anaphylaxis, rash, itching, urticaria). In addition, sometimes in the serum there is an increase in the content of bilirubin and liver enzymes.
|Coated Tablets||1 tablet|
|active substance :|
|calcium hydrophosphate dihydrate||53 mg|
|corn starch||11 mg|
|Opadry blue (hypromellose, macrogol, lactose monohydrate, aluminum blue lacquer, titanium dioxide)||6 mg|
|Opadry transparent (macrogol, hypromellose)||0.6 mg|
|carnauba wax and bee white||on 0,005 mg|
|active substance :|
|desloratadine micronized||0.5 mg|
|propylene glycol||100 mg|
|sodium citrate dihydrate||1.26 mg|
|sodium benzoate||1 mg|
|yellow dye "Sunsets"||0.023 mg|
|lemon acid||0.5 mg|
|disodium edetat||0.25 mg|
|flavoring №15864||0.75 mg|
|purified water||up to 1 ml|
Comparative studies have found that the dosage forms of desloratadine - tablets and syrup - are bioequivalent. The active substance of the drug "Erius" is well absorbed by the gastrointestinal tract and is determined in the plasma for 30 minutes after administration.
In the period from 2 to 6 hours (an average of 3 hours) after a single dose of the drug at a dose of 5 mg or 7.5 mg, the maximum concentration of desloratadine in plasma occurs.
The active substance of the drug "Erius" is extensively metabolized in the body, and only a small part of the dose taken is excreted in the urine (up to 2%) and feces (not more than 7%) as a glucuronide compound. The half-life is 20-30 hours.
The active substance of the drug "Erius" (desloratadine):
- prevents the development of allergic reactions and facilitates their course,
- has antiexudative and antipruritic actions,
- reduces capillary permeability,
- prevents the development of tissue edema and smooth muscle spasm,
- does not cause drowsiness,
- does not affect the central nervous system and the speed of psychomotor reactions.
"Erius" has a long (up to 24 hours) anti-allergic and anti-inflammatory effect by suppressing various allergic reactions.
The drug after oral administration begins to act within 30 minutes and up to one day.
Use during pregnancy and breastfeeding
During childbirth, the use of Erius is contraindicated, since there are no clinical data on the safety of the drug during this period.
The use of the drug "Erius" during HB is contraindicated, since the active ingredient (desloratadine) contained in the composition is excreted in breast milk.
Exceeding the recommended dose of the drug five times did not lead to the appearance of any symptoms. Clinical trials have shown that daily use by adults and adolescents of desloratadine at a dosage of up to 20 mg for two weeks did not cause statically or clinically significant changes in the cardiovascular system.
Clinical and pharmacological studies of the use of the drug "Erius" in a dose of 45 mg / day, which is 9 times higher than the recommended dosage, for 10 days found that the prolongation of the QT interval and the occurrence of serious side effects were not observed.
If there was an accidental use of the drug in large quantities, it is urgent to consult a doctor. First aid is washing the stomach and taking activated carbon.
It is released without a prescription. Shelf life - 2 years. Keep out of the reach of children at a temperature not exceeding 30 ° C.
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* - The average value among several sellers at the time of monitoring is not a public offer.