- Allegra (Telfast)
241 р. Average price online * 241 p.
Where can one buy:
Instructions for use
Fexofenadine - a drug with antihistamine and histaminergic action. Fexadine is another drug name. Available in the form of oblong peach-colored tablets with a risk on one side and an inscription containing the name of the drug and the dosage on the other. You can apply them with the consent of the attending physician.
Do not forget to click "Share" and leave your feedback on the drug!
Indications for the use of tablets Fexofenadine is an allergy of different origin:
- seasonal allergy to pollen , manifested as swelling of the nasal mucosa , tearing and itching;
- chronic and vasomotor allergies;
- allergic urticaria ;
- atopic dermatitis ;
- allergic dermatitis ;
- other dermatosis allergic origin.
Before using the drug, it is recommended to clarify the diagnosis, as well as to consult with an allergist regarding the appropriateness of using this particular drug.
Drug use and dosage
- with allergic rhinitis in children - 2 times a day, 30 mg, in adults - 120 mg once a day;
- for allergic skin rashes - once a day, 180 mg.
For patients with chronic form of renal failure, for any type of allergy, tablets are prescribed once in an amount of 30 mg.
According to official instructions from the manufacturer of the drug, it is not prescribed to young children (up to 6 years old inclusive). In addition, pills are prescribed with caution to pregnant women and nursing mothers. Acute and chronic kidney and liver diseases also require careful handling of this drug. In such situations, you can prescribe Fexofenadine only after a thorough examination of the patient by an allergist.
During the use of fexofenadine tablets, patients may feel symptoms that indicate the development of undesirable reactions of the body to the drug:
- sleep disorders, headaches and fatigue may develop on the part of the central nervous system;
- on the part of the gastrointestinal tract of the patient, dyspepsia and nausea can disturb, in rare cases, constipation develops during the course of Fexadin;
- on the part of the COP - a change in laboratory parameters, expressed in diagnoses of anemia and leukopenia;
- on the part of the respiratory organs - infections of the mucous membrane of the nose and throat, rhinorrhea, pain when swallowing, dryness in the nose and throat.
In rare cases, muscle aches or inflammation of muscle fibers, dysmenorrhea and an increase in AST are symptoms of undesirable reactions when using this antigastamine.
Composition and pharmacological properties
The tablets include the compound fexofenadine hydrochloride in an amount of 120 or 180 mg, as well as excipients that do not have a systemic effect on the body: titanium and silicon dioxide, magnesium stearate, cellulose, lactose monohydrate and talc.
The therapeutic effect of the drug is based on the ability of fexofenadine to selectively block the H1-histamine receptors, with the result that mast cells reduce the production and release of histamine in the tissue. Laboratory observations have shown the inability of the compound to act on calcium channels. Fexofenadine hydrochloride actively interferes with the transition of leukocytes to the conjunctival epithelium, and also slows down the basal expression of adhesive molecules on it.
After taking the pill, the effect occurs within 1-3 hours. At this time, the concentration of the active ingredient of the drug in the blood reaches its maximum indication, while 40-60% of fexofenadine is associated with its plasma. The active substance is derived through the urinary and digestive systems in almost unchanged form. The half-life is 14-15 hours. In case of liver diseases, the patient is over 65 years old, the half-life does not change or deviates slightly from the indicated ones. The only thing that can increase the half-life and concentration of the compound in the blood plasma is kidney disease and hemodialysis.
With an increase in recommended doses, patients may experience dry mouth and dyspeptic disorders. They may also be disturbed by dizziness and drowsiness. gastric lavage and laxatives are recommended as a method of eliminating symptoms. Hemodialysis in such situations is not used due to low efficiency.
Despite the lack of data on the negative impact on the fetus, the drug is taken during pregnancy and lactation only when the benefit to the mother many times exceeds the risk indicators for the fetus.
If necessary, take fexofenadine with antacid agents, which include aluminum or magnesium hydroxides, it is recommended to observe the two-hour interval between their intakes. With omeprazole capsules, fexadine tablets are compatible, so you can take them at the same time.
Pharmaceuticals, which include ketoconazole and erythromycin , increase the content of fexofenadine hydrochloride in the blood plasma, but this does not affect the frequency of adverse reactions and does not lead to overdose.
It is released without a prescription. Shelf life 3 years. Keep out of reach of children, in a dry place, at a temperature not exceeding 25 ° C.
(Leave your feedback in the comments)
* - The average value among several sellers at the time of monitoring is not a public offer.