Candidosis of the oral cavity and the corners of the mouth

Is it scary? Severe visceral forms of candidiasis and candidasepsis often begin with oral candidiasis in adults; therefore, special attention is now paid to the diagnosis and treatment of fungal diseases of the oral mucosa.

The factors causing infection with candidiasis and its forms:

Yeast-like anaerobic fungi of the Candida genus, which easily adapt and grow well in conditions of limited nutrition, cause x-ray and laser radiation, freezing and drying.

More than 80 species of Candida mushrooms are known. Most of them are safe and only a few cause candidal infection . The most pathogenic species are C. albicans and C. Tropicalis. When a defect occurs in the body's defense system, the mushrooms begin to actively proliferate and invade epithelial cells.

The factors that induce oral candidiasis are:

  • Mechanical and chemical microtraumas (carious teeth, dentures, irrational medical tactics during the rehabilitation);
  • Antibiotics and some other substances used in the production of canned food and food on mucous membranes and skin;
  • Metabolic disorders (iron deficiency, hypovitaminosis, endocrine pathologies, ovarian hypofunction, hypothyroidism);
  • Somatic diseases that reduce the body's resistance (immunity disorders, gastrointestinal diseases, gynecological pathology, etc.);
  • Candidate ;
  • Secondary immunodeficiency states;
  • Unsystematic antibiotic treatment.

The main symptoms of damage to the oral cavity and the red border of the lips (they are observed in 41.7% of patients with candidal pathology) are mucosal hyperemia, plaque, desquamation and puffiness. These symptoms are observed in any form of candidiasis: acute pseudomembranous candidiasis, acute atrophic candidiasis, chronic hyperplastic candidiasis, chronic atrophic candidiasis.

These forms are isolated on the basis of the clinical course. Localized candidiasis of the oral cavity are divided into stomatitis , glossitis and cheilitis, gums, gingivitis, etc.

Acute Pseudomembranous Candidiasis

thrush on tongue The most common form of candidiasis, which occurs even in newborns, infants, weakened by bronchitis and infectious diseases. In adulthood, the so-called "thrush" occurs in cancer.

Scope: tongue, sky, cheeks.

Complaints of patients: dry mouth, pain when eating, burning.

Clinical manifestations: plaque in the form of a curd film, which, with mild illness, is easily removed. Under the bloom an edematous, hyperemic surface is found. If candidiasis is triggered, then bleeding erosion is detected under a difficult-to-remove film.

Stage of the disease:

  • desquamative (areas of desquamation on the back of the tongue, the plaque is difficult to remove);
  • erythematous (tongue edematous, viscous, foamy);
  • infiltrative (difficult to remove bloom covered lateral surfaces of the tongue);
  • erosive (loose, gray-white coating, after removal, erosion is detected).

A photo

Click on the spoiler below to see what candidiasis looks in your mouth:

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Acute atrophic candidiasis

Arises both independently and after acute pseudomembranous form.

The main cause of occurrence is a side effect from taking antibacterial drugs, inhaled corticosteroids.

Complaints of patients: dryness and burning sensation in the oral cavity, the inability to move the tongue, the sensitivity of the mucous to any irritants.

Clinical manifestations: erythema spots without plaque or with bloom in large folds of the tongue, fiery-red color of the mucous membrane, the back of the tongue (when it is involved in the infection) is dark red, shiny, mucous cheeks and lips border thinned, sometimes crusts appear on lips.

Chronic hyperplastic candidiasis

It occurs in 75% of patients. The main contingent is people who take cytostatics, antibiotics, those who have a history of tuberculosis and blood diseases. Sometimes diagnosed in smokers and patients using dentures.

Complaints of patients: the perversion of taste, pain when taking spicy and acidic foods, dry mouth.

Clinical manifestations: the mucous is hyperemic, white plaques of various sizes can appear on the tongue and cheeks. In advanced cases, a rough, whitish-gray bloom occurs, which is removed with difficulty. Under bloom, bleeding erosion is detected. If the tongue is affected, nipple growth may occur.

Chronic atrophic candidiasis

It is diagnosed in patients with dentures, the elderly, with comorbid conditions: atrophic gastritis, diabetes, etc.

Complaints of patients: dryness and burning of the mucous membrane, redness, the release of viscous, sticky saliva.

Candidiasis of this form often affects the shell of the prosthetic bed, and in most cases these are upper jaw prostheses. Long-term current disease can cause atrophy of the papillary apparatus of the tongue.

Each of the above forms may be accompanied (or may occur independently) by mycotic diseases, candidal cheilitis and candidal gingivitis.

Mycotic zaeda, or candidiasis of the corners of the mouth, is a disease that is diagnosed in children who have the habit of sucking their finger or licking their lips, in adults with low bite. The main signs of zaeda are cracks in the corners of the mouth, erythema and easily removed whitish patina.

images Candida cheilitis is a disease in which the red rim of the lips is affected. Often, cheilitis affects the lower lip: first, individual bubbles appear on it, eventually merging into a white film. For cheilitis is characterized by severe itching, aggravated at night and a feeling of tightness.

If you do not treat candidiasis of the oral mucosa and the corners of the mouth, there are discomfort in the abdomen, headache and bad breath start to disturb, nausea and irritability occur. The pathological effect of fungi on the body is explained by the production of a number of toxic substances by microorganisms, the long-term cumulation of which disrupts the vegetative nervous system.


A fundamental point in the treatment is drug antifungal therapy , which can be systemic and local. Preparations for local treatment are divided into antimycotics and antiseptics.

The duration of treatment may vary, but on average it takes 2-3 weeks.

In western Europe and the CIS countries, the most commonly prescribed drugs are Miramistin, Cetylpyridinium Chloride, Triclosan, Chlorhexidine Bigluconate, Hexetidine, Sanguirythrin. Some of these antiseptics, in addition to weakening the pathogenic properties of fungi and helping to reduce the contamination of the oral cavity by fungi, also suppress inflammatory phenomena.

Cheap analogues Miramistina

Table "Drugs for the treatment of fungal infections of the oral cavity and the corners of the mouth":

A drug Assignment scheme
Tantum Verde (spray, solution, lozenges) Spray: 4-8 times a day for adults, every 1.5-3 hours, children 6-12 years old 4 times a day, up to 6 years - at the rate of 1 dose for every 4 kg of body weight.

Solution: 1 tablespoon (15 ml) of mouthwash or throat every 1.5-3 hours.

Tablets: one 3-4 times a day.

Novosept forte (spray, lozenges) 1 lozenge for sucking every 2-3 hours, spray irrigate mucous 3-4 times a day
Lugol solution Irrigation 3-4 times a day, mucous applications
Chlorhexidine digluconate 6-8 rinses for 1 minute (10 ml.)
Sanguirythrine 2-3 irrigations per day
Oralcept The drug is sprayed into the oral cavity every 4-6 hours.
Aqueous solutions of aniline dyes 3-4 times a day, duration 1-2 weeks (you can swallow and simultaneously sanitize the esophagus from mushrooms )
Fukortsin , brilliant green and fuchsin Applied to the treatment of mycotic jasper.
Local antimycotics
Kanesten (cream) Applications 2-3 times a day
Nystatin (ointment or water suspension) 4 applications a day for 30 minutes, rinses for 1 min. (at one time 5-10 ml.)
Amphotericin Rinse and application 4 times a day for 1 ml.
Clotrimazole (spray) Irrigation mucous
Candide or Clotrimazole 1% oral solution Check with the pharmacy before buying - special solutions are available that can rinse your mouth.
Antimycotics for systemic therapy
Fluconazole 50-100 mg. per day (duration - 10 days)
Itraconazole 100-200 mg. per day (duration 7 - 10 days)
Ketoconazole 200-400 mg. per day (duration - a maximum of 10 days)
Nizoral 10-14 days once a day in the morning during the meal at a dose of 200 mg. (control on liver and kidney functions is required)
Diflucan 10-14 days at a dose of 50 to 200 mg. in the morning
Orungal 15 days per capsule per day after a full meal During the treatment of oral candidiasis, concomitant diseases are necessarily treated. In addition, the reception is important:

  • Drugs that normalize the intestinal microbial flora;
  • Drugs with immunocorrective action;
  • Restorative remedies;
  • Medication, relieving inflammation and contributing to the restoration of the epithelium.

Drug therapy of oral candidiasis and the corners of the mouth should be combined with electrophoresis, phonophoresis, quartz therapy. Facilitates the course of candidiasis and relieves the inflammatory reactions of phytotherapy (the oral cavity is irrigated with broths of medicinal herbs - yarrow , sage, chamomile, and St. John's wort ).

As you can see, the arsenal of antifungal agents is very impressive. However, candidiasis is an insidious disease, and the therapeutic effect of treatment is not always observed. In addition, there is often a relapse of a yeast infection .

Therefore, do not self-medicate. A specialist (dentist, ENT, or, in extreme cases, a therapist) will prescribe treatment, take into account general somatic pathology and select rational in your particular case preparations.


  • Anna :

    And after treatment, the disease will not return?

    • Admin :

      Anna, in order to avoid relapses, it is necessary to observe oral hygiene, eat well and have no bad habits.

  • Katrin :

    Is Tonsillor a treatment for oral candidiasis in adults as well as Imudon?

    • Admin :

      Catherine, you can take Imudon as an adjunct to the main treatment, but not as the main remedy. As for tonsillore - in this particular case it is unlikely that he will help.

  • Christina :

    Does candidal cheilitis have strong unpleasant strong pain? And yet, I have not on the lip, but under the tongue right at the root. Treated gingivitis with a good tool, Stomatofita, helped me very quickly? Does it make sense and cheilitis them to rinse? Thank you for your reply.

    • Admin :

      Hello. Yes it is possible. Stomatofit is not intended to fight fungus. Try one of the things described in the article, but rather consult a doctor.

  • Nadya :

    Hello When yeast fungus in the mouth may not form ulcers on the tongue on the sides closer to the root?

    • Doc :


      Yes they can. But the sores are different, the reasons are different, it is better to show the specialist.

  • Olga :

    And which specialist should be addressed? Dentist? Therapist? Dermatologist?

  • Lena :

    Hello. Prescribed antibiotics pancef and augmentin in maximum doses, parallel-lactobacilli. On the 7th day of taking antibiotics candidiasis appeared on the lip, 5 more days left of the course. Isn’t it too destructive to add an antimycotic to treatment?

  • Vladimir :

    Hello. There were ulcers on the tip of the tongue and on the lower lip, very unpleasant. What to do, like I tried Futsis, but it took about 1 year and again.

    • Doc :


      If Futsis helped, it means the ulcers were caused by a fungus. The solution is to heal them again.

      To prevent it, brush your teeth regularly, lead a healthy lifestyle, eat properly.

  • Lyudmila :

    Good day. My daughter (17 years) after treatment of pneumonia in the throat on the tonsils appeared pustules, the doctor said to treat Candida, but there is no improvement. Diflucan 150 was prescribed today. Is this correct? How to take it?

    • Doc :


      That's right, Diflucan is applied once at a dosage of 150 mg.

      After that, you can continue to process, the result will be visible within a day, maybe two. If there is no improvement, see a doctor.

  • Irina :

    Hello, my child (4 years) has terrible lips (peel off, tear, crack) (((for 8 months, the doctors shrugged, were first treated in the hospital with sunshine, fukartsinom and belosalikom (didn’t cause anything, then treated at home with kanderm cream, yes it helped, but it no longer helps (it helped temporarily) now I smear vitaon oil, but I don’t want to go to our doctors (and I forgot to write, we even went to another city, we were assigned a grass cutter (I also helped temporarily) I gave up and now I am looking for help at least in the internet ((question: if we treat n About your principle choosing more benign drugs, the only thing is: is it necessary to give antimycotics in our case?

    • Doc :


      Doctors had to do an analysis for fungi, only after that you can prescribe antifungal.

      According to the symptoms and the reaction to the drugs, it is more like an autoimmune, although, again, without knowing the whole picture, it is difficult to make a diagnosis.

      Unfortunately, in most cases, autoimmune reactions are chronic. But, again, in most cases, it is possible to achieve remission with rare exacerbations.

      Do not give up, try other doctors, pick up drugs.

  • Elena :

    Hello! I am 57 years old, sakh. Diabetes type 2.
    They are worried about the almost non-passing bites in the corners of the mouth in the past six months, viscous mucus flowing down the back of the throat.
    They made a swab out of the pharynx for the presence of a fungus - positive.
    Pimafucin was prescribed, there are no improvements.
    What do you advise?

    • Doc :

      Good day,

      Use local antiseptics - Miramistin or chlorhexidine, handle the corners and rinse.

      You can try fluconazole, but you will need to consult a doctor to write a prescription and clarify the dosage that suits you best.

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