Pharmaceutical industry offers a lot of drugs for the treatment of nail fungus. All of them are characterized by varying degrees of effectiveness with respect to pathogens and variable conditions of use. So, on pharmacy counters you can find varnishes and solutions, ointments and creams, drops and pills against the fungus on the nails .
It is only a doctor who can determine which drug is better to use, because it is in his competence to determine the area of the affected areas, determine the type of fungus-pathogen and the general health of the person who requested it. Independently, you can only acquire prophylactic antifungal agents.
Consider the main ones:
In order to talk to the doctor "in the same language" at the moment when he will prescribe the treatment, we suggest to get acquainted with diverse preparations for the treatment of nail fungus on the legs . If it is impossible to visit the doctor, having information, you will be able to try to find the means to fight the disease.
Remember, all tablets have some toxicity to the liver, and their effectiveness from nail and skin fungus is lower than that of ointments, creams, varnishes and drops. Typically, tablets are prescribed for fungal infections of the throat , lungs, intestines, and other systemic mycoses.
Pills are prescribed for nails if the patient has problems with immunity, diabetes or age of 50 years. And only with a local drug (for example, drops ).
The action of the drug is aimed at suppressing the enzymes of the fungus, as a result of which the balance of active substances is disturbed, and the infection cells die.
Treatment with lamisil is used from 2 months, only during this time the tablets can completely cope with the infection. The longest treatment is the treatment of the nails on the big toes .
This drug is prescribed by a doctor in case of infection with dermatophyte fungi.
Due to the long-term use of pills, the following side effects may occur:
- lack of healthy appetite;
- lack of taste;
- upset stomach, possible vomiting;
- allergic reaction.
Who should refrain from pills:
- Pregnant and lactating mothers
- Patients with liver or kidney disease
- With increased sensitivity to the drug
The last 3 recommendations apply not only to Lamisil, but also to all tablets from the fungus.
How does it work? The second name of the drug - Diflucan . These are capsules that have been taken orally for onchomycosis since the mid-80s. After 0.5-1.5 hours after taking the drug, he finds in plasma. A stable concentration of 90% in the horny layer of the nail is achieved in 4-5 days. Since then, Fluconazole begins to destroy the cell membranes of fungi.
Who is suitable? Fluconazole effectively fights Candida albicans and Candida tropicalis, Microsporum spp., Tricho-phyton spp., Histoplasma capsulatum, Cryptococcus neoformans, Blastomyces dermatidis, Coccidioides immitis.
How to apply? If the nail area is affected, the capsules are taken weekly in a dose of 150 mg. Significantly slow down the development of infection in the second week of their use. But how long the treatment of nail fungus fluconazole will continue is unknown, because you need to drink the capsules until new nail plates grow. Normally, this process takes 6-12 months.
In advanced cases, dermatologists may prescribe fluconazole 50 mg. daily, or offer a pulse therapy.
Disadvantages and side effects. There were no significant changes in the hematopoietic system, kidneys and liver after prolonged use of capsules, and they are positioning the drug Fluconazole as a high-safety drug. However, the drug should be taken with caution in people with impaired liver and kidney function. In addition, it is impossible to take those who have a hypersensitivity to the components of the drug, those who take terfenadine, cisapride, astemizol (simultaneous use with fluconazal is prohibited). Also do not prescribe Fluconazole capsules to pregnant and lactating, because The drug is excreted in breast milk.
Terbinafin - tablets that are used against mold fungi. Already on the 8th week, the drug has an effect on the virus and fights it inside the nail bed. However, it is only a year later that the fungus can hit the tablet completely;
Itraconazole - tablets can be prescribed against almost all types of fungi: mold fungi, dermatophytes, various fungi of the Candida family. Also, the drug is known for the fastest effect.
Griseofulvin is a rarely used drug, outdated. Effective only against dermatophyte fungi;
Ketoconazole - a substance penetrates into the nail plate only at week 12, but after that it has an effective effect. Tablets are rarely recommended for dermatophytes and nail fungus due to the large number of side effects.
More preferred options:
How does it work? The preparation (varnish) is applied only on the nail plate affected by fungus. Destroys the fungus amorolfin substance contained in the lacquer (belongs to the newest chemical class of antimycotics). Amorolfin damages the cell membrane of fungi, which prevents them from biosynthesizing. Over time, the fungus and completely stops the livelihoods. Lac “Lotseril” after application to the nail plate is absorbed into it and the nail backing and begins to be active after 7-10 days. A huge plus of the drug is that it does not accumulate in the body and does not poison it: even after prolonged use, the concentration of amorolfine is insignificant.
Who is suitable? Amorolfin acts on most fungi: Scopulariopsis; Trichophyton; Candida; Pityrosporum; Mycrosporum; Alternaria; Epidermophyton; Cryptococcus; Sporothrix; Cladosporium; Hendersonula; Fonsecea; Coccidoides; Wangiella; Histoplasma, but not all.
The fungi Actinomyces and Propionibacteriumacnes amorolfin are not destroyed. Just for the diagnosis of the type of fungus and it is desirable to consult a doctor . Otherwise, treatment may not bring results and the money will be spent in vain. And, considerable: the drug will cost 1500-2500 rubles.
You can use "Loceryl" and as a prophylactic agent. To avoid infection, it should be applied to the nails a day before the visit to the sauna, bath, pool.
How to apply? Having bought “ Lotseril ” lacquer, you do not have to wrestle with what to treat the nail or how to apply lacquer. Complete with varnish comes a nail file (for processing nails), a tampon, an applicator for applying varnish.
The sequence of weekly nail treatment is as follows:
- Removal of the affected parts of the nail file (if the nails are long, it is better to cut them).
- Degrease the swab of the nail plate.
- Applying varnish with a special applicator (spatula). It is necessary to varnish the entire nail, and this should be done evenly.
- While the varnish will dry (at least 3 minutes), the bottle with varnish should be closed and the applicator cleaned with a swab.
A week later, the procedure of applying varnish is repeated, but the previous layer of varnish is removed with a swab.
The duration of the course for the treatment of toenails is from 9 to 12 months. It is believed that one bottle of varnish should be enough (according to the instructions, 2.5 ml. Enough for a 6-month treatment of three affected nails). Note that during treatment with varnish you can not build up the nails, as well as use detergent without gloves, if the fungus on his hands.
Side effects when using "Lotseril" rarely occur. This is mainly redness around the nail and burning. If after complete drying of the varnish it does not pass, then the drug should be canceled. Perhaps the body does not tolerate amorolfine. Do not prescribe Loceril lacquer to pregnant and lactating women, as well as to newborns and young children.
How does it work? Pharmacies present two forms of this drug: solution (drops) and cream . For onchomycosis, only the solution can be used, since cream is applied only on the foot affected by fungus. The main active component of exoderil is naftifine hydrochloride. It penetrates all skin layers and contributes to the destruction of the cell wall of the fungus. Excipients have an anti-inflammatory effect, so that itching and other symptoms of inflammation quickly disappear.
Who is suitable? Treatment of nail fungus with exoderil is reasonable only in the initial stages of the disease. It should be noted that "Exoderil", like the previous drug, destroys only certain types of fungi. Thus, daily application of the solution on the nail plate can relieve the feet only from mold fungi Aspergillus, dermatophytes Trichophyton, Microsporum, Epidermophyton, yeast and yeast-like fungi (Candida), Sporotrix schenckii.
How to apply? Drops for the treatment of nail fungus "Exoderil" are applied on a pre-cleaned nail plate. To accomplish this goal, it is possible to steam the feet in the bath with rubbed soap for 10-15 minutes. Then, after drying the legs (you can wipe with a towel or wait for natural drying), the nail is cut to the maximum, the affected part is also removed. After the preparatory measures, the solution is applied to the nails with a fungal infection.
Treatment of nail fungus exoderil can last up to 8 months. The term depends on the condition and number of nails affected by the fungus, as well as on the general well-being of the person. Up to 18 months of treatment will be required for individuals who have crossed the 60-year-old milestone, especially if the thumb is affected by the fungus. If this drug alone cannot cope with the fungus, then antibiotics and other antifungal agents are additionally prescribed.
After regrowth of a healthy nail, doctors advise to use the solution for another 3-4 weeks - to prevent recurrence. Note, the treatment with this drug is relatively inexpensive - a bottle will cost only 500 rubles.
Disadvantages and side effects. Exoderil solution can not be used during pregnancy, breastfeeding, in childhood, as well as if there are wounds on the feet and nails. The occurrence of local reactions such as burning and dryness of the skin, although they are considered to be side effects, are not a reason to cancel the treatment.
How does it work? This antifungal drug is used to treat mycoses and onchomycosis. Currently in pharmacies sold in the form of ointment. Treatment of nail fungus with clotrimazole can be carried out, although it is inconvenient and less effective than drops and varnishes.
For treatment, you need to apply the cream on the nail, cover with a cotton swab and glue the whole thing with a plaster. To carry out such a procedure twice a day, until a healthy nail grows.
The main active component is imidazole. It disrupts the synthesis of ergosterol, which is responsible for the smooth operation of the fungal cell membrane. As a result, the cell is damaged, its shell is broken and the fungus dies. Special enzymes also help to destroy the fungus, which in tandem with imidazole increases the concentration of hydrogen peroxide by several times. It also contributes to the destruction of fungi. The drug penetrates well into the epidermis and nail plates. In the keratin of the nail, it is found after 5-7 days from the start of the application.
Who is suitable? Clotrimazole has a wide range of lesions: it kills moldy, yeast-like fungi, dermatophytes.
Before applying the ointment or solution of the foot must be disinfected. A great option - soda-soap bath for the feet, which take 10-15 minutes. The alkaline soap base is detrimental to bacteria, but the soap must be thoroughly washed, otherwise it may reduce the effectiveness of Clotrimazole.
In order to better penetrate the nail into the nail, it is necessary to cut it as short as possible and file the top of the plate with a nail file so that it has a rough surface.
Read more: Instructions for use .
Disadvantages and side effects. There are not many contraindications to the use of a local antifungal agent:
- Allergy (with both clotrimazole and auxiliaries such as propylene glycol and polyethylene oxide).
- Pregnancy (only the first three months).
- Lactation (there is a possibility of clotrimazole in milk).
In rare cases, local reactions may occur: itching, redness of the skin, burning sensation. If they do not disappear for a long time from the use of the drug is better to refuse. Among the drawbacks of the drug is the inability to combine it with other antifungal agents, since Clotrimazole reduces their effectiveness.
How does it work? The main active component of the powder / cream for external use "Candida" is the same 1% clotrimazole. It acts on a fungus like other drugs: it damages the cell membrane, as a result of which the cell structure changes and its destruction is observed.
Who is suitable? Treatment of nail fungus Candida is effective if the causative agents are Candida yeast fungi, Torulopsis glabarata, Rhodotorula, dermatophytes, and mold fungi. Apply Candide powder at the final stages of treatment, when the inflammation has already been removed by Candide lotion, Candide cream or Candide Cream.
How to apply? The powder is applied to the nail plate from 1 to 3 times per day. Before that, you need to wash the feet and nails with soap with a neutral pH value, wipe them dry. The duration of treatment depends on the location of the lesion and the severity, but even after the regrowth of a completely healthy nail, the powder uses another 2 weeks. During treatment, it makes sense to treat the inner surface of the shoe with powder, which comes into contact with areas of skin affected by fungus.
In the absence of a pharmacy powder can buy Candid cream. Nails and skin before applying are treated as described above, then the cream is applied with a thin layer and rubbed with light movements. The nail should be cut short and, if possible, polished, so that the surface is slightly rough. So clotrimazon quickly penetrates the nail plate.
Disadvantages and side effects. Side effects (itching, burning, allergic reaction) are a signal to discontinue therapy and the need to change the drug.
Drug treatment of nail fungus is more effective than traditional. But the dermatologist should take up the selection of a specific drug, taking into account the individual characteristics of the patient. Of course, you can look at the pharmacy without consulting a doctor and buy the product most advertised on the Internet. However, in this case, you can not avoid side effects, because some drugs can not be taken to those who have problems of the gastrointestinal tract and endocrine system.