Treatment of mycosis with medicinal medicines (tablets)

Pharmaceutical industry offers a lot of drugs for the treatment of nail fungus. All of them are characterized by varying degrees of effectiveness in relation to pathogens and variational conditions of use. So, on drugstores you can find varnishes and solutions, ointments and creams, drops and pills against the fungus on the nails .

Determine which drug is best to use, can only a doctor, because in his competence to determine the area of ​​affected areas, the establishment of the type of fungus and the general health status of the person applying for help. Independently you can only purchase preventive antifungal agents.

The full list of drugs is here.

Consider the main ones:

To talk with a doctor "in one language" at the moment when he will prescribe the treatment, we suggest getting acquainted with the versatile drugs for the treatment of nail fungus on the legs . In case of impossibility to visit the doctor, having the information, you can independently try to pick up a means for fighting the disease.

Remember, all tablets have some toxicity for the liver, and their effectiveness from nail fungus and skin is lower than that of ointments, creams, lacquers and drops. Usually, tablets are prescribed for the fungus of the throat , lungs, intestines and other systemic mycoses.

Nails are prescribed tablets if the patient has problems with immunity, diabetes or age from 50 years. And only together with a local preparation (for example drops ).

Lamisyl (tablets)

The action of the drug is aimed at suppressing the enzymes of the fungus, as a result of which the balance of active substances is broken, and the cells of the infection are killed.

Treatment with lamilicum is used from 2 months, only during this time the tablets can completely cope with the infection. The longest treatment is associated with the nails on the big toes .

This drug is prescribed by a doctor in case of infection with fungi by dermatophytes.

Because of the long enough taking of tablets, these side effects can occur:

• Lack of healthy appetite;
• Lack of taste;
• Upset stomach, possible vomiting;
• allergic reaction.

Who should refrain from pills:

• Pregnant and nursing mothers
• Patients with liver or kidney disease
• With increased sensitivity to the drug

The last 3 recommendations apply not only to Lamizil, but to all the tablets from the fungus.

Fluconazole

How does it work? The second name is Diflucan . These are capsules that are taken internally with oncocomposes from the mid-1980s. After 0.5-1.5 hours after taking the drug, it detects in the plasma. Stable concentration of 90% in the stratum corneum of the nail is achieved after 4-5 days. From this moment "Flukonazol" begins to destroy the cell membranes of fungi.

Who will do? Fluconazole effectively fights with fungi Candida albicans and Candida tropicalis, Microsporum spp., Tricho-phyton spp, Histoplasma capsulatum, Cryptococcus neoformans, Blastomyces dermatidis, Coccidioides immitis.

How to apply? When the nail zone is affected, capsules are taken weekly at a dose of 150 mg. Significantly slow the development of infection in the second week of their use. But, how long will the treatment of the nail fungus with fluconazole continue? It is not known, because it is necessary to drink capsules until new nail plates are grown. Normally, this process takes 6-12 months.

In advanced cases, dermatologists may prescribe Fluconazole 50 mg. Daily, or offer pulse therapy.

Disadvantages and side effects. Significant changes in the hematopoietic system, kidneys and liver after long-term use of capsules were not detected by scientists, and they position the drug Fluconazole as a preparation of a high safety profile. However, the drug should be taken with caution to people with impaired liver and kidney function. In addition, it should not be taken to those who have an increased sensitivity to the components of the drug, to those who take terfenadine, cisapride, astemizole (simultaneous reception with fluconazal is prohibited). Also, capsules of Fluconazole are not prescribed for pregnant and lactating women. The drug is excreted in breast milk.

Yet:

Terbinafine is a tablet that is used against mold fungi. Already at week 8 the drug has an effect on the virus and fights with it inside the nail bed. However, the pills can completely kill the pills only after a year;

Itraconazole - tablets can be administered against virtually all fungi: mold fungi, dermatophytes, various fungi of the Candida family. The drug is also known for its fastest effect.

Griseofulvin is a fairly rare drug, obsolete. Effective only against fungi-dermatophytes;

Ketoconazole - the substance penetrates the nail plate only at week 12, but afterwards it has an effective effect. Tablets are rarely recommended for dermatophytes and nail fungus due to the large number of side effects.

More preferable options:

Loceril (lacquer)

How does it work? The drug (lacquer) is applied only to the nail plate affected by the fungus. Destroys the fungus contained in the lacquer substance amorolfin (refers to the newest chemical class of antimycotics). Amorolfin damages the cell membrane of fungi, which does not allow them to biosynthesize. Over time, the fungus also completely stops life. Lacer "Loceril" after applying to the nail plate absorbed into it and the nail substrate and starts to act actively after 7-10 days. A huge plus of the drug is that it does not accumulate in the body and does not poison it: even after prolonged use, the concentration of amorolfin is negligible.

Who will do? Amorolfin acts on most fungi: Scopulariopsis; Trichophyton; Candida; Pityrosporum; Mycrosporum; Alternaria; Epidermophyton; Cryptococcus; Sporothrix; Cladosporium; Hendersonula; Fonsecea; Coccidoides; Wangiella; Histoplasma, but not at all.

Mushrooms Actinomyces and Propionibacteriumacnes amorolfine are not destroyed. Just for diagnosing the type of fungus and it is advisable to consult a doctor . Otherwise, the treatment may not work and the money will be wasted. And, considerable: the drug will cost 1500-2500 rubles.

You can use "Loceril" and as a preventative. To avoid infection, it should be applied to the nails a day before the visit to the sauna, bath, swimming pool.

How to apply? Having bought a varnish " Лоцерил ", it is not necessary to puzzle over what to process a nail or than to put a varnish. In the complete set with a varnish there is a nail file (for processing of fingernails or nails), a tampon, the applicator for drawing of a varnish.

The sequence of weekly nail treatment is as follows:

1. Removal of affected sections of the nail with a nail file (if the nails are long, then it is better to trim them).
2. Degreasing the nail plate with a swab.
3. Application of varnish with a special applicator (scapula). To cover with varnish it is necessary all nail, and it needs to be done evenly.
4. While the varnish will dry (not less than 3 minutes), the vial with varnish should be closed, and the applicator should be cleaned with a swab.

After a week, the procedure for applying the varnish is repeated, but the previous layer of varnish is removed with a swab.

The duration of the course for the treatment of leg nails is from 9 to 12 months. It is believed that one bottle of lacquer should be enough (according to the instructions, 2.5 ml is enough for a 6-month treatment of three affected nails). Please note that during treatment with varnish, you can not build up your nails, or use gloves without gloves if the fungus is on your hands.

Side effects when using "Loceril" are rare. Basically, this is redness around the nail and burning. If after complete drying of the varnish it does not pass, then the drug should be canceled. Perhaps the body does not tolerate amorolfin. Do not prescribe laceril varnish for pregnant and lactating women, as well as for newborns and young children.

Exodermil

How does it work? In pharmacies are presented two forms of this drug: solution (drops) and cream . In case of onychomycosis, only the solution can be used. The cream is applied only to the foot affected by the fungus. The main active ingredient of exoderil is naphthifin hydrochloride. It penetrates into all skin layers and promotes destruction of the cell wall of the fungus. Auxiliary substances have an anti-inflammatory effect, so that the itching and other symptoms of inflammation quickly disappear.

Who will do? Treatment of a fungus of nails with a drug exoderil is reasonable only at the initial stages of the disease. It should be noted that Exoderil, like the previous preparation, destroys only certain types of fungi. Thus, the daily application of the solution to the nail plate can only relieve the feet of mold fungi Aspergillus, dermatophytes Trichophyton, Microsporum, Epidermophyton, yeast and yeast-like fungi (Candida), Sporotrix schenckii.

How to apply? Drops for the treatment of nail fungus "Exoderil" are applied to the previously cleaned nail plate. To achieve this goal, you can stag your feet in a bath with soapy soap for 10-15 minutes. Then, after drying the feet (you can wipe it with a towel or wait until it dries naturally), the nail is cut to the maximum, the affected part is also removed. After the preparatory measures, the solution is applied to the nails with a fungal infection.

Treatment of exotic nail fungus can last up to 8 months. The term depends on the condition and the number of nails affected by the fungus, as well as on the general well-being of the person. Up to 18 months of treatment will be required for people over 60 years old, especially if the thumb is affected by the fungus. If this drug alone can not cope with the fungus, then antibiotics and other antifungal agents are additionally prescribed.

After growing a healthy nail, doctors are advised to use the solution for another 3-4 weeks - to prevent relapse. Note, the treatment with this drug is relatively inexpensive - the bottle will cost only 500 rubles.

Disadvantages and side effects. Exodderil solution can not be used during pregnancy, breastfeeding, in childhood, and also if there are wounds on the feet and nails. The emergence of local reactions such as burning and dry skin, although they are considered side effects, are not the reason for canceling treatment.

Clotrimazole

How does it work? This antifungal drug is used to treat fungal infections and onychomycosis. At the moment, it is sold in pharmacies in the form of ointments. Treatment of nail fungus clotrimazole can be carried out, although it is inconvenient and less effective than drops and varnishes.

For treatment, you need to apply the cream to the nail, cover with cotton wool and cover the whole thing with adhesive tape. Carry out this procedure twice a day until the healthy nail grows.

The main active ingredient is imidazole. It disrupts the synthesis of ergosterol, which is responsible for the smooth functioning of the cell membrane of fungi. As a result, the cell is damaged, its shell is torn and the fungus is killed. To help to destroy the fungus and special enzymes, which in tandem with imidazole at times increase the concentration of hydrogen peroxide. It also helps to destroy the fungi. The drug penetrates well into the epidermis and nail plates. In keratin of nails, it is found after 5-7 days from the beginning of application.

Who will do? Clotrimazole has a wide range of lesions: it kills molds, yeast-like fungi, dermatophytes.

Before applying the ointment or solution, the feet must be disinfected. An excellent option - sodovo-soap tray for feet, which take 10-15 minutes. Alkaline soap base is detrimental to bacteria, however the soap needs to be washed off thoroughly otherwise it can reduce the efficacy of Clotrimazole.

In order for the medicine to penetrate the nail better, it should be cut as short as possible and processed with a nail-top plate so that it has a rough surface.

More: Instructions for use .

Disadvantages and side effects. Contraindications to the use of a local antifungal agent is not much:

• Allergy (both to clotrimazole, and to auxiliary substances such as propylegolic and polyethylene oxide).
• Pregnancy (only the first three months).
• Lactation (there is a probability of getting clotrimazole in milk).

In rare cases, local reactions may occur: itching, redness of the skin, burning sensation. If they do not disappear for a long time from the use of the drug is better to refuse. Among the shortcomings of the drug is the impossibility of combining it with other antifungal agents, as Clotrimazole reduces their effectiveness.

Candide

How does it work? The main active powder / cream component for external use of Candida is still the same 1% clotrimazole. It affects the fungus similarly to other drugs: it damages the cell membrane, as a result of which the structure of the cell changes and its destruction is observed.

Who will do? Treatment of Candida fungus is effective if the causative agents are yeast fungi Candida, Torulopsis glabarata, Rhodotorula, dermatophytes, mold fungi. Apply Candid powder at the final stages of treatment, when the inflammation has already been removed Candid lotion, Candide cream or Candid In cream.

How to apply? Powder is applied to the nail plate from 1 to 3 times a day. Before this, you should wash your feet and nails with soap with a neutral pH, wipe them dry. The duration of treatment depends on the location of the lesion and severity, but even after the growth of an absolutely healthy nail powder uses another 2 weeks. During treatment, it makes sense to treat the powder with the inner surface of the shoe, which contacts the affected areas of the skin with the fungus.

If there is no powder in the pharmacy, you can buy Candide cream. Nails and skin before applying are processed as described above, then the cream is applied in a thin layer and rubbed with light movements. The nail should be short-cut and if possible polished, so that the surface is slightly rough. So clotrimazone quickly penetrate the nail plate.

Disadvantages and side effects. Side effects (itching, burning, allergic reaction) are a signal to stop therapy and the need to change the drug.

Medicamental treatment of nail fungus is more effective than folk. But the choice of a specific drug should be a dermatologist, taking into account the individual characteristics of the patient. Of course, you can look into the pharmacy without consulting a doctor and buy the tool most advertised on the Internet. However, in this case, side effects can not be avoided, because some medications can not be taken by those who have problems of the gastrointestinal tract and the endocrine system.