|Loratadine Dosage Form||Analogs (ascending price)|
|Loratadine tablets|| Clarosens pills
|Loratadine syrup|| Klarotadin syrup
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Instructions for use
Loratadine is an antihistamine (antiallergic) medicine of the second generation .
The active ingredient of this drug blocks histamine receptors susceptible to allergens in the human body, thereby reducing the severity of allergic symptoms.
Compared with other drugs of similar action Loratadin:
- not addictive;
- does not have a hypnotic effect;
- has a long lasting effect.
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- allergic reactions accompanied by rhinitis , conjunctivitis and skin rashes;
- itching and redness of the skin after an insect bite ;
- angioedema ;
- allergic dermatitis ;
- atopic dermatitis ;
- chronic eczema;
- bronchial asthma ;
- pseudo-allergic reactions, such as the cold .
Dosage and administration
Loratadine must be taken at least one hour before meals. The nature of the pathology directly affects the duration of treatment - a course of treatment with Loratadine can last from several days to several weeks.
The maximum duration of the course is 1 month, but long-term administration of Loratadine must necessarily be agreed with the attending physician.
|Patient category||Single dose||Frequency of admission per day|
|Children from 2 to 12 years old (weighing less than 30 kg)||syrup: 1 tsp||1 time|
|tablets: half a pill||1 time|
|Children over 12 and adults||syrup: 2 teaspoons||1 time|
|tablets: 1 tablet||1 time|
|Adult Patients with Hepatic Insufficiency||syrup: not more than 1 tsp||1 time|
|tablets: half a pill||1 time|
- individual intolerance to the drug and its components (for example, lactase deficiency or syndrome of impaired glucose absorption);
- age of the child up to 2 years.
In adult patients: dizziness and headache, drowsiness, fatigue, decreased concentration, tachycardia, dry mouth, nausea, stomach pain, skin rash, bronchospasm, shortness of breath, focal baldness, anaphylactic shock, liver dysfunction.
In children: headache, drowsiness and lethargy or increased nervous irritability.
Composition and pharmacokinetics
- Loratadine - 10 mg per tablet
- Excipients: microcrystalline cellulose, potato starch, lactose, stearic acid
The drug is rapidly absorbed in the digestive tract, entering the blood within a quarter of an hour after ingestion. The drug effect occurs after 1-2 hours, then gradually increases, reaching maximum values after 8-12 hours, and persists throughout the day after taking Loratadine.
It is processed in the liver to form the active ingredient desloratadine . The half-life averages about 20-28 hours, but with alcohol poisoning this time doubles.
Excreted from the body with feces and urine. Does not accumulate and does not lead to addiction. It does not penetrate the blood-brain barrier and therefore does not directly affect the human nervous system, but passes into breast milk.
Loratadine can not be combined with the use of any alcoholic beverages, since alcohol reduces the drug's effectiveness of the drug and increases its negative impact on the liver. Alcohol consumption is possible 36 hours after the last dose of Loratadine.
It is undesirable to combine taking Loratadine with taking some antibiotics ( Erythromycin , Rifampicin), since this will lead to a weakening of the therapeutic effect from both Loratadine and antibiotics.
It is released without a prescription. Shelf life 3 years from the date of manufacture. Keep out of reach of children, at a temperature not higher than 25 ° C.
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