Analogues
Preparations based on fluconazole: Diflazone, Diflucan , Mikomaks, Nofung, Prokanazol, Fangiflu, Fluzol, Flukoside, Fluconorm, Flucoral, Forkan, Fungolone, Fluconazole , Flucostat , Fucis
Price
: 305 р. The average price online (1 capsule 150mg) * : 305 p.
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Instructions for use
Capsules of gelatin, filled with powder or powdery mass.
The main active substance, fluconazole - an antifungal drug, a group of triazoles. Effective against most fungal pathogens, including against candidiasis (thrush). The therapeutic effect is a violation of the synthesis of ergosterol and the cessation of growth of the cell membrane of fungi.
Excipients: silicon dioxide, magnesium stearate, talc, povidone, corn starch, lactose.
After taking the tablets, fluconazole is absorbed into the blood by 90%. The maximum concentration after taking 150 mg is achieved after 0.5-1.5 h. It penetrates well into all tissues and body fluids. In the stratum corneum of the epidermis, the dermis and the sweat fluid, high concentrations are reached, which exceed the serum levels. Constant values in the vaginal secretion are reached 8 hours after ingestion and are held at this value for at least 24 hours.
Indications
- Candidiasis in men
- Thrush in women
- Candidiasis of the abdominal cavity ( esophagus , intestine )
- Fungal infections of mucous membranes, for example, of the oral cavity
- Treatment of nail fungus (only if appointed by the attending physician, for example if the fungus is very neglected )
- Cryptococcal meningitis, cryptococcosis
- Mycosis of the skin (only if local medications do not help, it is prescribed by a doctor)
- Inguinal epidermophytosis
- Prevention of mycosis in patients with cancer, who are forced to undergo chemotherapy or radiation therapy
- Mycosis when taking cytotoxic drugs, in patients, after transplantation, use of antibiotics, with immunodeficiency.
How to use
For adults:
| Disease | Dosage | Duration of treatment |
| Vaginal candidiasis (thrush) | 150 mg | Once (one capsule of 150 mg) |
| Balanitis (male thrush) | 150 mg | Once (one capsule of 150 mg) |
| Skin mycosis | 150 mg once a week | 2-4 weeks |
| Peregrine lichen | 300 mg once a week | 2 weeks (rarely 3) |
| Nail fungus (onychomycosis) | 150 mg once a week | Until the healthy nail grows healthy |
| Cryptococcal infections | 400 mg once a day on the first day, then - 200-400 mg / day | Determine the doctor, you need a survey. Usually, 6-8 weeks. |
| Severe systemic candidiasis | It is possible to increase the dose to 800 mg / day | At least 2 weeks after the disappearance of symptoms or negative tests. |
| Severe candidiasis of mucous membranes | 100-200 mg / day | Defines the attending physician |
For children, the use of fluconazole is possible, but only the doctor determines the dosage and duration! Which doctor treats the fungus?
Contraindications
Mycosyst is contraindicated in the next. Cases:
- Hypersensitivity to one or more of the components of the drug.
- Lactation period (breastfeeding);
- Glucose-galactose malabsorption;
- Lactose intolerance, lactase deficiency;
After consulting a doctor:
- Hepatic and / or renal insufficiency;
- Pregnancy ;
- Violations of the electrolyte balance;
- Organic heart disease;
- Simultaneous reception of terfenadine and fluconazole in a dose of less than 400 mg / day;
- Simultaneous reception of drugs that cause arrhythmia.
Combination with other drugs
The drug does not combine with terfenadine and cisapride in a dose of over 400 mg / day. In this case, the risk of serious cardiac arrhythmias increases.
It is dangerous to combine with midazolam, t. This leads to a significant increase in the concentration of midazolam in the blood and the risk of developing psychomotor reactions.
Side effects
In rare cases, the following are possible:
Digestive system:
- flatulence,
- abdominal pain,
- nausea,
- Vomiting,
- diarrhea,
- Change of taste,
- Drug hepatitis.
Nervous system:
- dizziness,
- headache,
- Convulsions.
Allergic reactions:
- skin rash
- Pruritus
- Swelling of the face
- hives
Other:
- alopecia
- Hypertriglyceridemia
- Impaired renal function
- Hypercholesterolemia
- Hypokalemia
In case of an overdose, it is necessary to rinse the stomach and call an ambulance. Symptoms - nausea, vomiting, diarrhea; In severe cases, there may be hallucinations, paranoid behavior, convulsions.
Other
Capsules are dispensed without a prescription. Premature termination of treatment leads to relapse.
Keep in a place inaccessible to children, at a temperature of 10-25 degrees. Shelf life 5 years. The date of production or shelf life is indicated on the packaging.
Reviews
(Leave your feedback in the comments)
I wrote out a tablet, said if after one does not work - after a couple of days I repeat. Has passed with one, now all is good, repetitions were not. Лариса, 32 years old, Тюменская область
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