When the tactic is determined, the doctor can only prescribe the best drugs for the treatment of the nail fungus, but he does it after an advisory conversation with the patient. The reason for this - a huge number of local and systemic drugs, which differ in the form of release and, of course, the price.
Complete list of drugs, instructions, prices, reviews
A cheap remedy for foot nail fungus often causes side effects and has low effectiveness. Expensive domestic and imported drugs operate qualitatively, but in some cases, long-term treatment of them flies "a lot of money." Many positive reviews receive generics, which, unlike branded drugs, are of low cost, but they cope well with different kinds of fungi.
We offer to analyze some modern means of treatment of nail fungus . Keep in mind that the best remedy can be different depending on the disease. We will help you find your bearings, but we strongly recommend that you consult with your doctor before starting treatment. Perhaps a brief note on the drugs will help determine which of them would like to be treated.
Synthetic preparations of the azole group
The group of azoles includes preparations for local and systemic use, which are divided into triazoles and imidazoles. These antimycotics exert a fungistatic effect (do not allow mushroom spores to reproduce) and have fungicidal activity (kill fungal cells).
Preparations of the azole group are active against Candida spp. (Including Candida albicans, Candida tropicalis), Coccidioides immitis, Histoplasma capsulatum, Cryptococcus neoformans, Paraccoccidioides brasiliensis, Blastomyces dermatitidis. Poorly or not at all amenable to the effects of azoles Candida glabrata, Candida krucei, Aspergillus spp., Fusarium spp.
In Russia, the following agents for the treatment of nail fungi have been registered: fluoroconazole, terconazole, clotrimazole, miconazole , amikazole, bifonazole , fenticonazole, econazole , butoconazole, thioconazole, sulconazole, ketoconazole, voriconazole, fluconazole, itraconazole , etc. :
|A drug||Description||Mode of application||Contraindications|
|Clotrimazole||Principle of action: It blocks the synthesis of nucleic acids, ergosterol, which leads to damage to the membrane, and then to cell death. It is active against dermatophytes (Microspporum spp, Epidermophyton floccosum, Trichophyton spp.), Mold and yeast fungi (Candida spp., Torulopsis spp., Asppergillus spp., Cladosporium spp., Rhodotorula spp., Cryptococcus neoformans). Product: solution, cream, ointment.||2-3 times a day, rubbing into the nail plates damaged by the fungus. Before application: the legs are washed, disinfected (a soda-soap bath is suitable), the nails are cut short and for better penetration the medicines make their surface rough (only the affected area).||Pregnancy; Hypersensitivity to components|
|Candide||Principle of action Clotrimazole, the main active ingredient, disrupts the synthesis of ergosterol and the cell dies due to a change in the basic properties. Does not enter the systemic circulation. It is active against: yeast fungi Torulopsis glabarata, Rhodotorula, Candida; Dermatophytes, mold fungi. Form release: solution and cream for external use.||2-3 times a day, apply a cream or solution to the nail plate. Before application: wash the feet and nails in a soapy solution with a neutral pH.||Hypersensitivity to components.|
|Orungal||Principle of action: Prevents the synthesis of ergosterol, which leads to the destruction of the cell membrane. It is active against: yeast and yeast-like fungi (Candida albicans, Candida glabrata, Pityrosporum spp., Trichsporon spp., Candida krusei, Cryptococcus neoformans, Geotrichum spp.), Dermatophytes (Epidermophyton floccosum, Trichophyton, Microsporum). Form release: capsules of 100 mg of 6, 14, 28 pieces in a blister pack.||In case of fungal nail lesions, pulse therapy is recommended: 1 week - 2 capsules twice a day 2, 3, 4 weeks - break 5 weeks - 2 capsules twice a day 6, 7, 8 weeks - break 9 weeks - 2 capsules twice a day . Continuous course: 2 capsules once a day for 3 months.||Pregnancy, lactation. Simultaneous reception of other honey. Preparations (see the instructions on the link). With caution: children, persons with chronic cardiac, renal insufficiency, cirrhosis of the liver.|
|Nizoral||Principle of action: Suspends the synthesis of ergosterol, which leads to a change in the composition of the lipid components of the fungal cell, and it perishes. It is active against: yeast fungi (Candida, Cryptococcus, Pityrosporum, Thorulopsis), dermatophytes (Microsporum sp., Trichophyton sp, Epidermophyton floccosum). The form of release: tablets on 200 mg, a cream, shampoo (at a lesion of a pilar part of a head) .||The tablet is taken with meals once a day. The cream is applied 1-2 times a day (depending on the severity of the disease). Duration of treatment - 6-12 months (depends on the rate of regrowth of the nail plate).||Hypersensitivity to the components of the medication is for the cream. Chronic liver disease, concurrent use of certain drugs, lactation, pregnancy - for tablets|
Synthetic preparations of allylamines group
This group includes synthetic antimycotics naphthyfine , butenafin (from locally used), as well as terbinafine . Local preparations are indicated if the lesion is less than 50%, nails are infected singly, and the matrix is not affected. Allylimins tablets are prescribed if many nails are affected, a distal-lateral type of fungal infection is diagnosed, and if local therapy does not work.
|A drug||Description||Mode of application||Contraindications|
|Lamisil||Principle of action: Terbinafine affects the initial stage of biosynthesis of sterols and thus leads to a deficiency of ergosterol and to cell death. It is active against dermatophytes (highest to Trichophyton, for example, T. verrucosum, T. rubrum, T. mentagrophytes, T. violaceum), yeast fungi Candida albicans. Apply if: more than 50% of the nail is affected, the matrix is affected, the fungus has captured more than 2-3 nails, the nail dystrophy has started. Form release: spray, pills, cream.|| Spray : 1-2 times a day, spraying on the nail plate in an amount sufficient for moisturizing. Cream : on a fingernail and adjoining sites 1-2 times a day a thin layer slightly rubbing.
Tablets : 250 mg each. Per day (1 tablet) - for adults. For children - ½ table. At weight from 20 to 40 kg., ¼ table. With weight less than 20 kg.
Uno : once (see instructions)
| For the spray: hypersensitivity to any of the components of the drug, children's age. For the cream: hypersensitivity to the ingredients in the cream, age up to 12 years.
Tablets: age to 2 years, allergy or sensitivity to constituent ingredients, chronic kidney or liver disease.
|Exodermil||Principle of action The active ingredient - naphthyfine hydrochloride - slows the action of ergosterol. In addition, the drug from nail fungus Exoderil has an anti-inflammatory effect and quickly relieves itching and inflammation symptoms. Heals from yeast fungi , dermatophytes (microsporium, trichophyton, epidermorphin), mold fungi. Product: solution and cream|| The cream is applied once a day to the fungal nails with a thin layer. Pre-treatment: cleansing nail plates, cutting nails, washing and thorough wiping feet. The solution is applied to the nail, as well as to nearby healthy tissues (1 cm at the edges of the affected area) once a day. Pre-treatment: drops from the fungus of the nail exuderil are applied to the ground with a fillet and maximally trimmed nail. Treatment can be carried out with a special agent, loosening the nail plate.
Duration of treatment - from 6 months.
|Exoderate from nail fungus on the legs can not be used when hypersensitivity to naphthyfine, during pregnancy and breast-feeding. Also, a contraindication is the presence of a wound surface.|
Synthetic preparations of the morpholine group
Antifungal agents in this group contain amorolfin , which changes the structure of the cell membrane and subsequently kills the fungus or prevents it from multiplying. A representative of this group is a remedy for nail fungus Lotseril. It is applied to the damaged nail plates of the toes only once a week. Laceril lacquer is active against the following species of fungi: Candida, Pityrosporum, Microsporum, Epidermophyton, Alternaria, Cryptococcus, Trichophyton, Cladosporium, Fonseceae, Wangiella, Coccidioides, Hendersonula, Scopulariopsis, Histoplasma, Sporothrix. The solution also works as well as other local preparations: it penetrates to the nail plates and disrupts the biosynthesis of sterols. The active substance - amorolfine in the nail is detected already after 24 hours after using the varnish, and on 7-10 days the maximum concentration of the drug is reached. Nail fungus on legs Lotserilomizlechivaetsya for 9-12 months (this time from the first application to the regrowth of a healthy nail plate). They use it as follows: dipped the spatula for application in the solution and carried it over the entire surface of the nail, waiting for complete drying. There are several nuances:
- Pre-treatment is necessary: the surface of the nail is treated with a nail file attached to the varnish and degreased with an alcohol swab.
- Hygienic requirements should be observed in order not to promote the spread of fungal infection: the scapula is removed from the bottle without touching the neck of the bottle; The neck is treated before sealing with an alcohol swab. Similarly come with a shovel. Lotseril from the nail fungus is completed with a nail file and a tampon: they are used only once.
Systemic absorption of the drug is negligible, so among the contraindications to use only hypersensitivity to the components of the drug, pregnancy, the period of breastfeeding, children's age. You can buy nail polish Loceril in pharmacies, but you need to be ready to see next to the name of the drug from the nail fungus Lotseril price is quite high: from 1300 rubles per bottle 2.5 ml (the average price can be found here .).
Other antifungal agents
In addition to the above, there are other medicines related to arene groups, glucan synthesis inhibitors, aniline dyes, boric acid derivatives, bis-quaternary ammonium salts and others. In this group are also herbal preparations and derivatives of undecylenic acid. Let us briefly consider these means of treating the nail fungus.
|A drug||Description||Mode of application||Contraindications|
|Mikoseptin||The active ingredient is undecylenic acid. This substance is active against dermatophytes Epidermophyton, Trichophyton and Microsporum. Product: ointment.||Apply twice a day to a clean and dried nail plate. It can be used as a compress: the ointment is applied to the bandage and applied to the nail. The treatment schedule is 4 to 6 weeks. When the symptoms disappear, the ointment continues to be applied according to the scheme: 1 week - treatment once a day, 2, 3, 4 weeks - treatment every other day.||Age to 2 years, the presence of open wounds, sensitivity to derivatives of undecylenic acid.|
|Nitrofungin||The active ingredient is undecylenic acid. Has an antiseptic, disinfecting effect, does not allow to reproduce yeast fungi. Product: solution.||Until the symptoms disappear completely, the nail plates are treated 2-3 times throughout the day. For prevention (if the family is ill), the solution is applied 2 times a week. Special instructions: if there is irritation, the drug is diluted with water (1: 1).||Children under 2 years old, allergic, hypersensitive to the components of the drug.|
|Mycosis||The preparation of vegetable origin, is registered as the goods of chemist's additional assortment. The active ingredient is a rye enzyme. Product: Serum. In the kit, there are 10 disposable nail files.||Two-time application of whey during the day. The course of treatment is at least 4 weeks.||Age up to 4 years.|
Some use Formidron from nail fungus. This drug primarily helps with excessive sweating of the feet. In the case of the fungus, its efficacy can only be said at the initial stages of the disease. The Formidron solution is rubbed into the surface of the nail with a cotton swab every 2-3 days.
Candida saved me simply!
A couple of years ago I had a problem - I strongly sweated my legs, so I could not wear light clothes. We were advised to buy a formridron! The best remedy I've tried! Helps awesome! + Helps with sweating feet!
My story with a nail fungus began in 2009. After the nail growth in an expensive salon on all nails got out the fungus. Nails just exfoliated from the bed. This horror I have not seen. The doctor diagnosed Candida Albicans. The trips to the doctors resulted in 20000 UAH. A pile of tablets, ointments, lotions and other nonsense. The liver screamed "guard." After that, folk remedies went into action. There was a domestosis, acetic essence, a mixture of tablets, vinegar and other rattling ingredients. So it lasted 7 years. The force was no longer looking at the hands. Not only was the nails visible Horrible, so even the skin began to cloud. And just recently a neighbor came and saw how I was sitting on my fingernails in some kind of regular solution and I was almost crying. She advised to trim the nails as much as possible and to drip with the formidone, which costs 12 UAH in the pharmacy. For a month, there was no trace of the fungus. But at once I will warn - the agent aggressive and very much dries and burns a skin round a fingernail. It is better to grease with any antimicotic ointment after shadridron it will be absorbed. And try to get less on healthy skin. I wish everyone good luck in the fight against the enemy.