It can be considered a complete analogue of methylprednisolone.
37 р. Average online price * 37 r. (pack of 3 ampoules)
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Instructions for use
Prednisolone (Prednisolonum) is a synthetic drug belonging to the group of glucocorticosteroids.
Antiallergic, anti-inflammatory, immunosuppressive agent, superior in activity to cortisone, and hydrocortisone 3-4 times. Analogs are: dekretin, medopred, inflanafran, prednisol, prelnigexal.
Prednisolone injection is a colorless (or yellowish) water soluble substance.
Available in ampoules, sealed in cartons of 3,5,6,10 and 20 pieces (30 mg of prednisone sodium phosphate / 1 ml solution for injection).
The drug for intravenous or intramuscular administration, refers primarily to the means of emergency care, used in the following cases:
- in severe allergic reactions ( angioedema , anaphylactic shock , an attack of bronchial asthma );
- in case of acute renal-hepatic failure that developed in the postoperative or postpartum period;
- with severe rheumatic fever;
- shock condition (cardiogenic, burn, traumatic shock);
- swelling of the brain;
- in acute hepatitis;
- in acute adrenal insufficiency
- in case of poisoning with aggressive liquids causing burns to the mucous membranes.
In addition to emergency care, the drug is used in complex therapy in the treatment of malignant tumor processes, autoimmune, chronic pulmonary and dermatological diseases.
Indications for the use of prednisone are also some cardiac pathologies, in particular, exudative pericarditis and rheumatoid myocarditis, as well as a decrease in threshold excitation in patients with implanted heart stimulant.
The drug is used in hematology - in the treatment of leukemia, anemia, MDS, pathologies associated with bone marrow dysfunctions.
Many patients, far from medicine, believe that "hormonal" drugs cause irreparable harm to the body, and therefore either stop taking it prematurely or do not take the medicine at all.
Such an approach may, in some cases, lead to dire consequences, many of which are irreversible.
With a correctly calculated dosage prescribed by a specialist, taking into account the indications and state of health, the drug will not cause serious complications. Remember that absolutely all drugs (including those of natural origin) have side effects that are much more serious than those that cause corticosteroids. Therefore, you should take prednisone (medopred) precisely according to the scheme, which was made by the attending physician.
Dosage and duration of treatment is prescribed individually.
Prednisolone is administered intravenously or intramuscularly. In case of intravenous administration, the drug is first administered by a jet, then transferred to the drip mode.
The following treatment regimen is generalized because it does not take into account the patient’s health status and the presence of relative contraindications:
with acute adrenal insufficiency - from 100 mg to 200 mg one-time, within 3-14 days;
in the treatment of bronchial asthma - from 75 mg to 675 mg per treatment course (from 3 to 16 days);
in shock , accompanied by a drop in blood pressure, 50-150 mg are injected in a jet , in severe cases the dose is increased to 400 mg (the maximum daily dose is 1000 mg);
in case of complications after surgery and acute poisoning , the drug is administered at 25-75 mg per day (in severe cases, it can be increased to 300-1500 mg per day).
for rheumatoid arthritis , 75 to 125 mg per day is indicated for a 10-day course of treatment;
in severe form of hepatitis, 75-100 mg per day is prescribed for a course of treatment for 7–10 days;
for internal burns of the respiratory and digestive organs from 75 to 400 mg per day for 5-18 days.
If the drug cannot be administered intravenously, intramuscular injections are prescribed. After stabilization of the state, prednisone is prescribed in capsules (tablets) with a gradual decrease in dose.
There is also intraarticular injection , but it is performed only by a doctor, the dosages are selected only individually for each patient.
In emergency (shock) conditions, prednisone is administered without taking into account contraindications, as a means of emergency care.
Do not use the drug in therapeutic courses for severe hypertension, gastric ulcer and duodenal ulcer, reflux disease, osteoporosis, Cushing's disease.
Contraindications are infections such as chickenpox, herpes, shingles, as well as the active form of tuberculosis, pregnancy (first trimester, in particular), lactation.
Weight gain, potassium deficiency (hypokalemia), growth retardation in children, Cushing's syndrome (moon face), increased blood pressure, thrombosis, muscle atrophy, thinning of the skin, a violation of the digestive process, nausea.
On the part of the nervous system, such manifestations as depression, hallucinations, reduced visual acuity, general weakness, headache are possible.
The above symptoms are possible, but they do not appear in every case. In general, the drug is well tolerated by patients, even with prolonged use.
The drug is not recommended to take simultaneously with salicylates, barbiturates, diuretics, cardiac glycosides. When taking the medicine, it is necessary to monitor blood pressure indicators, donate blood for sugar, examine feces for hidden blood, make an X-ray (for arthritis and bursitis).
With intravenous prednisone, the effect comes instantly, a little slower with intramuscular injections. The drug binds to plasma proteins (globulins and albumin), is metabolized in the liver (mostly), and in the kidneys. Duration of exposure 24-36 hours.
Terms of sale
The drug is available on prescription.
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