Treatment of allergic pathologies is not complete without the use of antihistamines - this rule applies to all age groups of patients.
Let's try to objectively compare 4 popular drugs:
(In alphabet order)
All rassomtrennye drugs do well with the manifestations of allergies and dermatitis allergic nature, including atopic. They block histamine receptors, thereby removing symptoms.
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"Diazolin" . Inexpensive remedy that quickly copes with an allergic reaction, eliminates the swelling of soft tissues, blocks the attacks of itching. The drug can also be used by patients suffering from bronchial asthma, as it has an effect on bronchial receptors.
"Loratadine . " One of the most effective and popular drugs for the treatment of allergies, referring to the drugs of the new generation (second). Unlike many other drugs with similar properties, Loratadin has almost no sedative effect, retains its therapeutic effect for a long time, and is taken independently of the meal.
"Suprastin . " A medicinal product with pronounced antihistamine properties and high efficacy in combating various types of allergies. Allowed for children from 1 year old (pills need to be crushed and added to food).
In addition to the antihistamine effect, it has a spasmolytic ability of weak or moderate intensity (that is, relieves spasms of smooth muscle fibers).
Tavegil . Drug for eliminating allergy symptoms and combating dermatological diseases. It has a high degree of absorption, with the result that the therapeutic effect occurs 15-30 minutes after taking the drug.
Comparative table of drug characteristics
|Generation of antihistamines ( more )||one||2||one||one|
|Active substance||Mebhydroline nazisilat||Loratadine||Chloropyramine Hydrochloride||Clemastine|
|Cost at the time of publication *||78r (10 pieces)||64r (10 pieces)||122r (20 pieces)||134r (10 pieces)|
|The rate of onset of the therapeutic effect||1-2 hours||15-30 minutes||15-30 minutes||15-30 minutes|
|Duration of the result||5-6 hours||24 hours||3-6 hours||4-8 hours|
|Frequency of admission (per day)||1-3 times||1 time||2-3 times||2-4 times|
|Half-life from the body||6-8 hours||12-20 hours||6-8 hours||2-5 hours|
|Sedation||there is||Not||there is||there is|
|Relation of drug absorption with food intake||Is taken during or after meals.||Is taken regardless of the meal||Accepted with meals.||Taken before meals|
|Interaction with other substances||Enhances the effect of hypnotics, not compatible with alcohol||Alcohol and some drugs reduce the effectiveness of loratadine.||Enhances the effect of hypnotic drugs and neuroleptics||Enhances the effect of hypnotics and alcohol|
|Use in childhood||From 2 years||From 2 years||From 1 year||Syrup from 1 year, tablets from 6 years|
|Use during pregnancy||The instructions are vaguely indicated that the drug is not recommended. In fact, the recommendations are the same: apply only if the potential benefit to the mother exceeds the possible risk to the fetus. Only a doctor can determine this.|
|Use during lactation||Should decide the question of the timing of the termination of breastfeeding before taking antihistamines.|
|Release form||Pills and dragees||Tablets and syrup||Tablets and solution for injection|| Tablets and solution for injection
(syrup is not available at the time of writing)
|Shelf life||3 years 6 months||4 years||5 years||5 years|
Comparing the cost, do not forget that you need a different number of tablets per day.
As for the sedative effect, opinions differ, on one of the patients one substance has a stronger effect on someone else. All drugs of the 1st generation are sedative to some extent.
When you can not take these drugs
All tested drugs should not be taken during pregnancy and lactation.
And everyone has a standard contraindication - hypersensitivity to the components of the drug. In other words - individual intolerance.
Diazolin - can not be taken for epilepsy, pyloric stenosis, angle-closure glaucoma, cardiac arrhythmias, prostatic hypertrophy, gastric or duodenal ulcer, acute inflammation of the gastrointestinal tract.
Under the supervision of a physician for renal or hepatic failure.
Suprastin - disorders of the kidneys or liver, angle-closure glaucoma, prostatic hyperplasia, urinary retention, pathology of the heart and blood vessels.
Elderly patients can take "Suprastin" only under the condition of constant medical supervision.
* - The average value among several sellers at the time of monitoring is not a public offer.