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Instructions for use
Form: pills in a blister pack, 500 mg per pill.
The main active ingredient: valacciclovir (lat. Valacyclovirum).
Manufacturer: Public Joint-Stock Company Farmak. Kiev, Ukraine.
Valogard is a modern remedy for the treatment and prevention of herpes of various types. The main active component of this medicine is the ester substance acyclovir. The drug is most effective against the following herpes viruses: Herpes simplex of the first and second types, Varicella zoster, Epstein-Barr virus, HPV 6, cytomegalovirus.
In adults, Valogard tablets are used in the following cases:
- for the prevention of herpes infection of the genital type of a healthy partner;
- to prevent recurrence of herpes infections of the skin and mucous membranes;
- in the process of treating the skin and mucous membranes affected by the herpes simplex virus ;
- to combat the disease of shingles .
Adults and children over 12 years old take the drug as an effective prevention of the onset of cytomegalovirus infection and other herpes virus infections after undergoing an organ transplant operation and to prevent kidney transplant rejection.
Dosing and Administration
Tablets are taken orally (by mouth), regardless of the food.
Валогард принимают в течение недели, по 3 раза каждый день. For the treatment of tinea Vagard taken during the week, 3 times every day. In this case, the recommended dose of the drug - 1000 mg.
занимает, в среднем, 5 дней. Treatment with herpes simplex pills takes, on average, 5 days. In severe cases, the course of taking the drug is extended to 10 days. Valogard is taken 2 times a day, and its recommended dose is 500 mg.
герпесной инфекции лечение продолжают ещё от 3 до 5 дней. To prevent the reappearance of herpes infections, treatment is continued for another 3 to 5 days. Dose - 500 mg once a day. For patients with immunodeficiency, it is recommended to take tablets of 500 mg twice a day.
Prevention of infection with genital herpes. People infected with the herpes virus (relapses occur no more than 9 times a year) are recommended to take Valogard 500 mg once a day regularly throughout the year.
Prevention of herpes infections after organ transplants. For adults and children over the age of 12 years, the drug is prescribed immediately after the operation. Dose - 2 g twice a day.
врачи рекомендуют уменьшать обычную дозу препарата (напрямую зависит от типа нарушения работы почек) и поддерживать необходимый для их организма водный баланс. For patients with various impaired renal function, doctors recommend reducing the usual dose of the drug (directly depends on the type of renal impairment) and maintaining the water balance necessary for their body.
дозировку корректирует врач после обследования. Patients with impaired liver function and elderly patients (over 60 years of age) should be adjusted by the doctor after the examination.
- Hypersensitivity or intolerance to the components that make up this medical drug.
- Human immunodeficiency virus (if the content of blood cells that react to immunity to infections is less than 100 / μl).
- Age up to 12 years (in cases of prevention of herpes infection after surgery for transplantation and CMV infection).
- The drug is strictly contraindicated for pregnant women and persons under 18 years of age.
Valogard should be taken with caution during lactation, in patients with renal and hepatic insufficiency, as well as in elderly patients, people diagnosed with HIV infection and at risk of dehydration.
Pregnancy and lactation
The drug is strictly prohibited during pregnancy. During the breastfeeding period, tablets should be taken with extreme caution.
In cases of exceeding the permissible dose of the drug, the following signs of overdose may occur: vomiting, various changes in consciousness, hallucinations, a state of excitement, acute renal failure.
Patients who exceed the recommended dosage of Valogard should consult a doctor as soon as possible and constantly be under medical supervision.
Often (from 1/10 to 1/100) there is a headache, nausea.
Rarely: dizziness, hallucinations, diarrhea, abdominal pain, skin rashes and itching, renal impairment.
Valogard tablets can influence the process of driving a vehicle.
Composition and pharmacokinetics
One tablet contains 500 mg of the active substance valacciclovir, as well as auxiliary components: microcrystalline cellulose, silica, povidone, magnesium stearate, crospovidone, titanium dioxide, potassium aluminum silicate, acetylated mono-and diglycerides.
Immediately after taking the drug is rapidly absorbed into the blood from the gastrointestinal tract, turning into 2 active ingredients: acyclovir and valine. In the case of taking the drug in a dose of 1000 mg, the degree of absorption of acyclovir is 54%, regardless of food intake. The highest level of valaciclovir in the blood plasma can be diagnosed approximately 3 hours after taking the pill. It is 4% of the total concentration of the substance acyclovir. The drug is excreted by the kidneys, mainly in the form of acyclovir and the metabolite of acyclovir.
The shelf life of the drug is 2 years after the date of its manufacture. Tablets should be stored in a dry and out of reach of children, away from direct sunlight. Recommended air temperature: up to 25 ° C.
Valogard is a prescription drug and is released from pharmacies only with a doctor’s prescription.
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